Assay Dynamic Range for DBS: Battles on Two Fronts

Abstract

BioanalysisVol. 3, No. 20 Special Focus: Dried Blood Spots - EditorialAssay dynamic range for DBS: battles on two frontsYifan Shi & Hongliang JiangYifan Shi† Author for correspondenceCovance Laboratories Inc., Bioanalytical Chemistry, 3301 Kinsman Boulevard, Madison, WI 53704, USA. Search for more papers by this authorEmail the corresponding author at yifan.shi@covance.com & Hongliang JiangHuazhong University of Science & Technology, Tongji School of Pharmacy, 13 Hangkong Road, Wuhan, Hubei 430030, ChinaSearch for more papers by this authorPublished Online:20 Oct 2011https://doi.org/10.4155/bio.11.234AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInReddit View articleKeywords: dilutiondried blood spotLC–MS/MSregulated bioanalysissensitivityBibliography1 Liang X, Li Y, Barfield M et al. 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Denver, CO, USA, 5–9 June 2011.Google ScholarFiguresReferencesRelatedDetailsCited ByOfficial International Association for Therapeutic Drug Monitoring and Clinical Toxicology Guideline: Development and Validation of Dried Blood Spot–Based Methods for Therapeutic Drug MonitoringTherapeutic Drug Monitoring, Vol. 41, No. 4State of the Science in Dried Blood Spots1 April 2018 | Clinical Chemistry, Vol. 64, No. 4The use of mass spectrometry to analyze dried blood spots22 September 2014 | Mass Spectrometry Reviews, Vol. 35, No. 3Capillary microsampling in the regulatory environment: validation and use of bioanalytical capillary microsampling methodsLars B Nilsson, Martin Ahnoff & Ove Jonsson13 March 2013 | Bioanalysis, Vol. 5, No. 6A bioanalytical strategy utilizing dried blood spot sampling and LC–MS/MS in discovery toxicology studiesLorell Discenza, Mary T Obermeier, Richard Westhouse, Timothy V Olah & Celia J D’Arienzo21 May 2012 | Bioanalysis, Vol. 4, No. 9Development and validation of a fully automated online human dried blood spot analysis of bosentan and its metabolites using the Sample Card And Prep DBS SystemJournal of Chromatography B, Vol. 885-886 Vol. 3, No. 20 Follow us on social media for the latest updates Metrics Downloaded 814 times History Published online 20 October 2011 Published in print October 2011 Information© Future Science LtdKeywordsdilutiondried blood spotLC–MS/MSregulated bioanalysissensitivityAcknowledgementThe authors would like to thank Douglas Fast at Covance for his thoughtful discussion and critical reviews of the manuscript.Financial & competing interests disclosureY Shi is employed by Covance and H Jiang is a former employee. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. No writing assistance was utilized in the production of this manuscript.PDF download