ASSA14-14-05 Initial experience of occluding special type patent ductus arterioses using the Amplatzer vascular plug I

Abstract

<h3>Background</h3> Occluders licensed for clinical use are not fit for some special Krichenko E patent ductus arterioses (PDA). The Amplatzer vascular plug I (Plug I) has not been licensed for use for closure of PDA. We report our initial experience to occluding special type PDA with the Plug I. <h3>Methods</h3> Patients referred with small and long Krichenko E PDA 1–3 mm in diameter underwent occlusion using this Plug I, this is a single lobe device of single layer Nitinol mesh for short vessel landing zones. All cases underwent pre-, intra- and post-procedural echocardiography at the completion of the procedure the next day and at a 30-day follow-up visit. Device sizing for device waist diameter and length was based on aortography. <h3>Results</h3> 26 patients with a median age of 5 years (range 6 months – 32 years) and a median weight of 19 kg (range 7–67 kg) underwent successful PDA closure. The median ductus diameter was 2.2 mm (range 1–3 mm). Both transpulmonary (22/26) and transaortic approaches (4/26) were used. No persistent patency was observed after 24 h and one month. <h3>Conclusions</h3> The Plug I Makes it easy to close some Krichenko E PDAs. Smaller delivery catherter profile and symmetric cylindrical device shape allow for use for small and long Krichenko E PDA 1–3 mm in diameter and small patients through transaortic approaches. Broader experience is required to further delineate device and patient selection as well as to document its long-term efficacy and safety.