Abstract
Prevalence of graft occlusion is high after coronary artery bypass grafting (CABG). Routine use of aspirin after CABG reduces graft failure and ischemic complications. The benefit of concomitant clopidogrel administration remains a controversial issue.
Highlights
Background/Introduction Prevalence of graft occlusion is high after coronary artery bypass grafting (CABG)
Aims/Objectives We sought to evaluate the impact of use aspirin plus clopidogrel versus aspirin alone on graft patency and adverse cardiovascular events 18 months after CABG
In this single-centre prospective randomized study, 200 consecutive patients undergoing elective CABG were randomly assigned to two groups: 97 patients received aspirin 300 mg (A) and 103 patients received aspirin 100 mg plus clopidogrel 75 mg (AC)
Summary
Background/Introduction Prevalence of graft occlusion is high after coronary artery bypass grafting (CABG). Aims/Objectives We sought to evaluate the impact of use aspirin plus clopidogrel versus aspirin alone on graft patency and adverse cardiovascular events 18 months after CABG. Method In this single-centre prospective randomized study, 200 consecutive patients undergoing elective CABG were randomly assigned to two groups: 97 patients received aspirin 300 mg (A) and 103 patients received aspirin 100 mg plus clopidogrel 75 mg (AC).
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