ASPIRIN ALLERGY: ITS RELATIONSHIP TO CHRONIC INTRACTABLE ASTHMA

Abstract

Article1 May 1947ASPIRIN ALLERGY: ITS RELATIONSHIP TO CHRONIC INTRACTABLE ASTHMASIDNEY FRIEDLAENDER, M.D., SAMUEL M. FEINBERG, M.D., F.A.C.P.SIDNEY FRIEDLAENDER, M.D.Search for more papers by this author, SAMUEL M. FEINBERG, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-26-5-734 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFor some time we have recognized a rather characteristic type of asthmatic patient whose symptoms are of unusual severity and chronicity, and who in addition presents a history of hypersensitivity to aspirin. Aspirin allergy has long been recognized, and a number of reports of severe reactions, some fatal, have appeared in the literature.1 The present discussion, however, does not deal particularly with these acute reactions to aspirin, but rather with the relationship of this drug hypersensitivity to the etiology of the chronic asthma which these individuals display.We have reviewed the findings in 45 private patients who fall into this...Bibliography1. LAMSONTHOMAS RWR a. : Some untoward effects of acetylsalicylic acid, Jr. Am. Med. Assoc., 1932, xcix, 107. b. DYSART B. R.: Death following ingestion of five grains of acetylsalicylic acid, Jr. Am. Med. Assoc., 1933, ci, 446. c. FRANCIS, NATHAN, GHENT O. T. BULLEN S. S.: Death from ten grains of aspirin, Jr. Allergy, 1935, vi, 504. CrossrefGoogle Scholar2. PRICKMANBUCKSTEIN LEHF: Hypersensitivity to acetylsalicylic acid (aspirin), Jr. Am. Med. Assoc., 1937, cviii, 445. CrossrefGoogle Scholar3. 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LANDSTEINER K: The specificity of serological reactions, 1945, Harvard Univ. Press, Cambridge, Mass. Google Scholar11. KERN RA: Asthma and allergic rhinitis due to sensitization to phthalic anhydride. Report of a case, Jr. Allergy, 1939, x, 164. CrossrefGoogle Scholar12. FEINBERGWATROUS SMRM: Atopy to simple chemical compounds—sulfonechloramides, Jr. Allergy, 1945, xvi, 209. CrossrefGoogle Scholar13. COOKE RA: Infective asthma: indication of its allergic nature, Am. Jr. Med. Sci., 1932, clxxxiii, 309. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication July 25, 1946.From the Division of Allergy, Department of Medicine, Northwestern University Medical School, Chicago, Ill.The experimental work mentioned in this paper was supported by a grant from the Upjohn Co., Kalamazoo. Michigan. 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SMITH, M.D., F.A.C.P.ON THE RELATION BETWEEN DRUG ALLERGY AND ATOPYThe Stability of Acetylsalicylic Acid in SuspensionAspirin sensitivity—Experimental studies 1 May 1947Volume 26, Issue 5Page: 734-740KeywordsAllergy and immunologyAspirinAsthmaDrugsEtiologyFallsHypersensitivity ePublished: 1 December 2008 Issue Published: 1 May 1947 PDF downloadLoading ...