Abstract

Aspirin (Acetylsalicylic acid) is used widely in human and veterinary as cardiovascular prophylaxis and as anti-inflammatory, anti-clotting agent and to decrease cancer risk. But there is a deficiency of information about its effects on androgenic studies histology of the testes, kidneys and livers and reproductions. In this paper we tried to collect the information about it deleterious toxicity effect on male rat reproduction and the reason of its side effects. Our finding shows that Aspirin has deadly effect the production of sperm, decrease the testis weight, decrease the production of testosterone and also affect the blood profile. Effect of aspirin on the male reproductive system may be due to being a Prostaglandins inhibitor, and According to all our findings probably it indicates that aspirin have deleterious effect on reproduction and the blood chemistry of male rats

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