Abstract
Acetylsalicylic acid was first synthesised by Dr FeIix Hoffman on 10th August 1897 and Aspirin was born. It quickly became the best-known pain killer in the world and in the 120 years since this event, aspirin has continued to attract interest, innovation and excitement. Set within the walls of the preserved ruins of Rudolf Virchow’s lecture hall at Charité, within Berlin’s Museum of Medical History, the International Aspirin Foundation’s 28th Scientific Conference served to facilitate international, multi-disease, multidisciplinary discussion about the current understanding of aspirin’s mechanisms of action and its utility in modern medicine as well as ideas for future research into its multifaceted applications to enhance global health.In addition to the delegates in Berlin, 300 medical doctors at the 19th Annual Scientific Congress of the Chinese Society of Cardiology were able to join the cardiology sessions from Taiyuan, Shangxi province via a live streaming link to and from China. This led to useful discussion and allowed a truly international perspective to the meeting.
Highlights
Conference ReportMATCH 2004, PRoFESS 2008 and SPS3 2012, all failed to increase efficacy but increased the risk of bleeding, CHANCE, which randomised 5,170 patients from 114 hospitals focused on early, short-term, optimised dual antiplatelet therapy (within 24 hours) to reduce the risk of new stroke at 3 months for clopidogrel-aspirin treatment in acute minor stroke or high-risk transient ischaemic attack (TIA)
The first session, an update on cardiovascular disease (CVD) and stroke: East meets West was chaired by Professor Junbo Ge, who expressed his delight at joining the conference and working together to tackle CVD, which is the number one killer in China
A combination of aspirin and clopidogrel for 21 days is recommended for patients with minor stroke or high-risk transient ischaemic attack (TIA) within 24 hour of onset [10]
Summary
MATCH 2004, PRoFESS 2008 and SPS3 2012, all failed to increase efficacy but increased the risk of bleeding, CHANCE, which randomised 5,170 patients from 114 hospitals focused on early, short-term, optimised dual antiplatelet therapy (within 24 hours) to reduce the risk of new stroke at 3 months for clopidogrel-aspirin treatment in acute minor stroke or high-risk TIA. While numerous trials have been carried out on the role of aspirin in acute treatment and the secondary prevention of CVD, there are relatively few in the area of primary prevention and most have been done among those at lower risk of CVD events This is because of the large scale that is required for these studies and the need for long-term follow-up. At fairly regular intervals, medications need to be reviewed with the patient in order to update where the patient is on the risk to benefit spectrum
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