Abstract

Objective There is currently no consensus regarding the optimal management of acute suppurative thyroiditis (AST) secondary to pyriform sinus fistula (PSF). To investigate the benefits and adverse events of aspiration with or without lavage for the treatment of AST secondary to PSF. Subjects and methods This was a retrospective analysis of consecutive patients with AST secondary to PSF who were admitted at the Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University between August 2012 and December 2018. Clinical information, procedural data, and imaging data were analyzed. Results Seven patients (five women; mean age, 16.9 ± 6.3 years; range, 8-26 years) were included. The patients most presented with anterior neck pain and swelling (n = 7), fever (n = 7), or odynophagia (n = 5). Six cases of AST occurred on the left side of the thyroid and 1 on the right. All patients had thyroid abscess. AST was diagnosed by ultrasound-guided needle aspiration cytology in all cases. PSF was diagnosed during the inflammatory stage in five patients and during the quiescent stage in two. All patients were treated with empiric antibiotics. Needle aspiration without lavage was performed in three cases. Needle aspiration with lavage was performed in four cases. Repeat aspiration was performed in three cases. All patients recovered completely, with no procedure-related complications. During 18.3 ± 7.8 months of follow-up, AST recurred in one case. Excision of the PSF was performed in another case. Conclusion Ultrasound-guided aspiration with or without lavage had a good treatment effect and without adverse events for the management of AST secondary to PSF.

Highlights

  • Acute suppurative thyroiditis (AST) is an extremely rare disease representing 0.1-0.7% of all cases of thyroid diseases [1,2,3]

  • There is currently no consensus regarding the optimal management of AST secondary to pyriform sinus fistula (PSF)

  • This study aimed to investigate the benefits and adverse events of aspiration with or without lavage for the treatment of AST secondary to PSF

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Summary

Introduction

Acute suppurative thyroiditis (AST) is an extremely rare disease representing 0.1-0.7% of all cases of thyroid diseases [1,2,3]. We sought to investigate the benefits and adverse events of aspiration with or without lavage for the treatment of AST secondary to PSF. Patients with suspected AST (presenting with anterior neck swelling, pain, and fever) underwent blood routine, infectious index, thyroid function, ultrasound (US), US-guided aspiration cytology, and pus bacterial culture.

Results
Conclusion
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