Aspiration Pneumonia Due to Clozapine-Induced Sialorrhea

Abstract

Introduction Clozapine is a second-generation antipsychotic, which use is limited to treatment-resistant cases of schizophrenia. Sialorrhea, a well-known side effect of clozapine, occurs in 31–54% of patients receiving clozapine therapy (1). Patients may complain of both daytime and nighttime drooling (the “wet pillow” sign). Here, we report the case of a young man who developed aspiration pneumonia due to clozapineinduced sialorrhea.