Abstract

Bronchopulmonary allergic mycosis is a group of diseases characterized by type 1, 3 and 4 hypersensitivity reactions to fungi from the environment. Aspergillus fumigatusmay be a cause of different clinical entities: asymptomatic colonization, Aspergillus bronchitis, Allergic bronchopulmonary aspergillosis (ABPA), invasive aspergillosis. ABPA occurs primarily in patients with asthma and cystic fibrosis(CF). Patients withCF are especially prone to fungal respiratory infections because of altered fluid thickness and mucus composition. Thus, Aspergillus fumigatusis the most frequent fungal pathogen and is found in the sputum of up to 58% of patients with CF, the diagnosis of ABPA in CF patients remains difficult because of shared clinical features. It has been associated with more severe worsening and lung damage, so timely diagnosis and specific therapeutic management are of utmost importance.We are presenting two clinical cases with different magnitude of pulmonary involvement, where diagnostic difficulties and variable outcomes were encountered

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