Abstract
Treatment of AIDS involves the use of the cocktail of drugs that make up the antiretroviral therapy. Its logistic control is monitored by a computerized national system of dispensation, the Logistic Control System of Medication (SICLOM). This study aimed to investigate, by means of SICLOM data, the use of antiretroviral therapy in patients treated at two University Hospitals in the state of Rio de Janeiro. A cross-sectional study was conducted with sociodemographic and dispensation data collected from SICLOM. The evaluation of drug ownership was done by calculating the Proportion of Days Covered (PDC). Five hundred and thirty-eight patients of both genders with active registration in SICLOM and over 18 years of age were included. The ART most used in both hospitals was lamivudine, considering the total of 58 different schemes identified. The mean of possession of groups was 88% (± 0,16). The factor associated with possession of drugs was the ART scheme, with PDC of 91% (p<0,001) for rescue schemes. This study confirmed that SICLOM was a reliable source to establish the profile of the population assisted.
Highlights
Apesar dos avanços no tratamento, a pandemia da AIDS ainda é um problema de saúde pública
Treatment of AIDS involves the use of the cocktail of drugs that make up the antiretroviral therapy
Its logistic control is monitored by a computerized national system of dispensation, the Logistic Control System of Medication (SICLOM)
Summary
Foram incluídos no estudo 538 usuários assistidos no hospital A (25%) e B (75%) (Figura 1) cuja caracterização está apresentada na Tabela 1. Foram encontrados 58 esquemas diferentes e a maioria da amostra recebia esquemas de primeira linha de tratamento (Tabela 1). No hospital B, foram encontrados 46 esquemas, dos quais cinco foram classificados como de primeira linha, 11 como de segunda linha, 15 como de resgate e 15 como não classificáveis segundo o protocolo clínico (Tabela 2). Aproximadamente, 47% (199) da amostra do hospital B estavam em uso de esquemas de 1a linha, 40% (168) usaram esquemas de 2a linha de tratamento, enquanto 8% (30) usaram esquemas resgate, os outros 6% (24) usaram esquemas não classificáveis. Avanços de conhecimento sobre os ARV permitiram que os pacientes permanecessem mais tempo em uso de esquemas de 1a linha de tratamento[5,6,7]. Escolaridade (410) Sem instrução e menos de 1 ano 1 a 3 anos 4 a 7 anos 8 a 11 anos 12 anos ou mais
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