Abstract
Objective: Our aim was to determine the significance of aspartate aminotransferase platelet ratio index (APRI), neutrophil to lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) in predicting gestational diabetes mellitus (GDM) at first trimester screening in a retrospective study of pregnant women.
 Method: In this study, a retrospective analysis of pregnant women (n=216) screened at the antenatal clinic and diagnosed with gestational diabetes between 24-28 weeks of gestation was performed. APRI score, NLR and PLR were calculated in the blood of these pregnant women in the first trimester and compared with the results of patients in the control group (n=250).
 Results: The ROC -analysis for APRI yielded an AUC value of 0.489 (p=0.684). Maternal age was found to be an independent risk factor for GDM. The risk increased 1.162-fold with increasing maternal age (p < 0.001). The optimal cutoff value for NLR was 3.55, sensitivity was 65%, specificity was 49%, and the area under the ROC curve was 0.544.
 Conclusion: In the results we compared with those of the control group, we found no significant change in APRI value and PLR. However, we found that NLR has a predictive value for GDM.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
