Asociación entre temperatura corporal al ingreso a urgencias y mortalidad intrahospitalaria en pacientes sépticos, estudio de cohortes

Abstract

ObjectiveTo estimate the relationship between body temperature on admission and hospital mortality. DesignProspective analytical observational cohort study conducted between February and July 2017 on patients diagnosed with sepsis, and who were admitted to fourth level hospital. Digital temperature was taken, and the outcome was in-hospital mortality. FrameworkThe association between body temperature and hospital mortality in sepsis is controversial. Studies show that fever increases oxygen consumption and worsens multi-organ dysfunction, and the counterpart is, that it helps control pathogens. PatientsPatients admitted consecutively over a 6-month period to the Resuscitation room of Méderi Hospital Universitario Mayor with sepsis and met the inclusion and exclusion criteria. Interventions and measurementsThe axillary digital temperature was taken upon admission, using a standardised digital thermometer, guaranteed and with a calibration guarantee). ResultsThe relative risk for in-hospital mortality in septic patients, according to hypothermia vs no-hypothermia was 1.58, 95%, confidence interval 0.85-2.84, P=.056. The incidence of death in hypothermic patients was 4.2 per 100 hospital admission days, compared to an incidence of death in non-hypothermic patients of 2.6 per 100 patient hospital admission days. This was not statistically significant (P=.056). ConclusionsAlthough there is a non-statistically significant trend between presenting with hypothermia and mortality, there was no direct association in this cohort between body temperature and in-hospital mortality. In this population, the factors most associated with in-hospital mortality were pulmonary foci and septic shock.