Abstract
ObjectiveTo examine the association between maternal colonization with serotype III group B Streptococcus (GBS) and premature rupture of membranes (PROM) in comparison with other GBS serotypes. Material and methodWe performed a retrospective cohort study. GBS strains were serotyped in pregnant women. The women were divided into 2 groups: group I consisted of patients with a positive vaginal or urinary culture for GBS serotype III and group II consisted of patients with a positive culture for serotypes Ia, Ib, II, IV, V or VI. ResultsThere were 135 GBS isolations. Group 1 included 43 pregnant women and group 2 included 92 pregnant women. PROM occurred in 27 patients in group I (62.7%) and in 17 patients in group 2 (18.4%) (RR = 3.3; 95% CI, 1.2-7.4; p < 0.05). ConclusionsVaginal colonization with serotype III of GBS was associated with a 3-fold increase in the risk of PROM.
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