Abstract

ObjectiveTo describe the relationship between oxidative stress present in bronchial asthma and the role of acute and chronic effects of physical exercise on airway inflammation and antioxidant defense system balance based on the current scientific literature on this subject. Search strategyRelevant scientific articles were searched in the PubMed, Scopus, Embase and Ovid databases. Study selectionWe used international articles published in English, Portuguese or Spanish that provided an objective approach within the epidemiological, physiopathological and physiological and biochemical context of the article. Synthesis of resultsAsthmatic bronchial inflammation is directly associated with the execution of physical exercise, endogenous oxidant production and the antioxidant defense system. ConclusionsPhysical exercise exacerbates bronchial constriction and increases oxidative stress. However, in the long term, it provides anti-inflammatory and antioxidant enzyme adaptations. The number of studies that describe the antioxidant adaptations in asthma is ephemeral.

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