Asian Pacific Society of Cardiology Consensus Statement on Management of Coronary Artery Disease in Adults with Late Complications of Kawasaki Disease

Abstract

Despite reductions in the mortality of Kawasaki disease with advances in its treatment, a proportion of patients still develop coronary artery dilatation that may persist even into adulthood. These lesions carry an increased risk of myocardial ischaemia and infarction. However, published clinical guidelines on the management and long-term follow up of patients with these late complications of Kawasaki disease are limited. The Asian Pacific Society of Cardiology convened an expert panel to review the available literature and develop consensus recommendations to guide clinicians in this area. The panel developed statements on the assessment and risk stratification of coronary artery disease, investigations for follow up, as well as considerations around treatment of stenotic lesions with medical therapy, percutaneous coronary intervention and coronary artery bypass grafting. Each statement was voted on by each panel member and consensus was reached when 80% of experts voted ‘agree’ or ‘neutral’. This process resulted in the development of consensus recommendations to guide cardiologists and internists in the follow up and management of patients with coronary artery lesions as a late complication of Kawasaki disease.