Сase of Progressive Fibrodysplasia Ossificans in Combination with a Rupture of Cerebral Arterial Aneurysm and Hyperparathyroidism

Abstract

A rare clinical observation of a 24-year-old patient with clinical and radiological manifestations of Fibrodysplasia Ossificans Progressiva, combined with rupture of saccular cerebral aneurysm and hyperparathyroidism, is presented. A characteristic feature of this case was a combined pathology of cerebral vessels with Fibrodysplasia Ossificans Progressiva, the first manifestations of which appeared after intracranial haemorrhage with the development of severe motor neurological deficiency. It was accompanied by articulate and severe spastic syndromes, tough muscle and joint contractures, and the signs of Vitamin D deficiency and hyperparathyroidism were found later.