Abstract

A three-year accumulation of data obtained from the analysis of more than 1,000 blood samples indicated that the average plasma ascorbic acid level of the patients in this hospital was less than .40 mg %. The lowest results, averaging .20 mg %, were obtained during the months of April, May and June and the highest during October and November when an average of .59 mg % was achieved. These data on ascorbic acid and others on various nutritional essentials which will be described in subsequent reports indicated that a large mental institution is an exceptional laboratory for conducting studies of human nutrition and a project has been started to make use of this opportunity. The regulated routine of the majority of the patients, the supervision of the dietary intake, and the choice of age and sex from the large numbers available make it possible to have better controls than is ordinarily so easily available.A modification of the Mindlin and Butler1 method was used to determine the plasma ascorbic acid. No c...

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