Ascending pyelonephritis in dogs induced by ureteral dysfunction (author's transl)

Abstract

Abnormal ureteral peristalsis was induced in 39 mongrel dogs by passing a 2 per cent formalin solution into the left ureter. Vesicoureteral reflux was induced in the dogs by fastening a polyethylene tube at each ureteral orifice. In order to create infection, a piece of gauze smeared with canine feces was sewn to the trigone.After observation of 4 to 323 days, the dogs were sacrificed. In 87.1 per cent of the dogs, pyelonephritis was present in the left kidney. In only 7.7 per cent, pyelonephritis was seen in the right kidney.These results suggest that vesicoureteral reflux and abnormal ureteral peristalsis are necessary conditions for inducing experimental pyelonephritis.