Abstract
Detection of monoterpenoid ascaridole and other terpenoids in the genus Chenopodium from the East Mediterranean. Distribution of ascaridole in leaves of 13 species medicinal plant belonging to the genus Chenopodium was examined with the help of the GC MS method. cis Ascaridole was found as a major peroxy monoterpenoid (up to 46.9 %) in the oil. Three minor isomers: cis isoascaridole (1.1 6.4 %), trans ascaridole (1 2 %), and trans isoascaridole (1 2 %) were also detected. The biological activities and biosynthesis of ascaridole are further discussed. The results on Ascaridol and the major volatiles and semi volatiles of wild species belonging to the genus Chenopodium provide important information on biologically active monoterpenoid compounds and volatile metabolites biosynthesized in wild medicinal plants growing in the East Mediterranean.
Highlights
In the past several decades, natural peroxides have been isolated from a wide variety of plants, and marine organisms[1, 2]
The essential oils of leaves of 13 species medicinal plant belonging to the genus Chenopodium were isolated by normal SD
According to the obtained data cis-ascoridole varied from 4.2 % in C. betrays to 46.9 % in C. ambrosioides, and cis-isoascaridole was present in all studied species, and varied from 1.1 % in C. urbicum to 6.4 % in C. murale
Summary
In the past several decades, natural peroxides have been isolated from a wide variety of plants, and marine organisms[1, 2]. Various plant parts of different species of Chenopodium have been traditionally used in the treatment of several disorders[9]. Herb C. ambrosioides is a plant widely known in popular medicine as antihelminthic, vermifuge, emmenagogue and abortifacient[11, 12]. It is used for the treatment of digestive, respiratory, uro-genital, vascular and nervous disorders, for metabolic disturbances such as diabetes and hypercholesterolemia, and as sedative, antipyretic and antirrheumatic[13]. Kishore et al.[14] described the fungitoxicity of chenopodium oil against dermatophytes such as Aspergillus fumigatus and Cladosporium trichoides
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