Abstract

Asbestos disease pathogenesis: The long and short of it Jean Pfau and Kinta Serve explore a critical and novel hypothesis concerning the size of fibers in asbestos disease pathogenesis. A mineral fiber is defined as having an aspect ratio (length/width) that is greater than three, but the mineral is only considered asbestos if it also has certain commercially-valuable qualities like durability and tensile strength. Only six silicate-based commercial minerals are officially called ‘asbestos’. However, currently, to be counted as asbestos, a fiber also must be long enough to be seen with light microscopy. Why?

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