AS OCT as a tool for presumptive diagnosis of conjunctival amyloidosis and follow-up

Abstract

Clinical diagnosis of conjunctival amyloidosis is quite often difficult, given the diverse clinical manifestations. We report a rare case of primary conjunctival amyloidosis in a 26-year-old male patient in whom a presumptive diagnosis of amyloidosis could be made based on anterior segment optical coherence tomography (AS OCT) and was confirmed histopathologically from the excised specimen. AS OCT revealed multiple, hyperreflective, linear, wavy subepithelial stromal deposits suggestive of amyloidosis. Systemic evaluation by an internist and a hematologist was negative. Herein, we highlight the possible role of AS OCT in diagnosing conjunctival amyloidosis and propose its role as a follow-up tool thus far not described in literature.