Abstract

Contrast-induced nephropathy is a major cause of morbidity and mortality associated with percutaneous coronary intervention. Recently, several reports have shown that N-acetylcysteine is effective to reduce the occurrence of contrast-induced nephropathy, but some reports could not confirm this. Different dosages of N-acetylcysteine may lead the conflicting results, and thus we examined the effect of N-acetylcysteine at >3600 mg in total dosage on serum creatinine levels after coronary intervention.

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