Abstract
BackgroundTo compare the postoperative safety, efficacy, predictability, visual quality and biomechanics after implantation of Artisan vs. Artiflex phakic intraocular lenses (PIOLs).MethodsPubmed, Embase, Cochrane Library were conducted up from January 2000 to February 2020. Comparative clinical studies reporting in accordance with the eligibility criteria were included in this meta-analysis. The pooled weighted mean differences (WMDs) and odds ratios (ORs) with corresponding 95% confidence intervals were calculated.ResultsComparative trials with myopia patients were selected in this review. The pooled WMD and OR estimates statistical significance in terms of postoperative best corrected visual acuity (BCVA), efficacy, postoperative spherical equivalence (SE), predictability, contrast sensitivity and mean intraocular higher-order aberrations (HOA) (mm) for a 6-mm pupil, manifesting that Artiflex PIOL showed evident beneficial effect for correcting myopia compared to Artisan PIOL. There was no significant difference in the incidence of complications between the two groups.ConclusionBoth of two techniques were safe and effective for myopia and compared to Artisan PIOL, Artiflex PIOL had significant improvement in efficacy, predictability, contrast sensitivityand HOA, except safety and complications in the treatment of moderate to high myopia.
Highlights
To compare the postoperative safety, efficacy, predictability, visual quality and biomechanics after implantation of Artisan vs. Artiflex phakic intraocular lenses (PIOLs)
The phakic intraocular lens implantation has been proved to be a safer technique for correcting myopia ranging from − 6.00D to − 20.00D compared to excimer laser techniques, showing significant advantages on the maintaining of best corrected visual acuity (BCVA), contrast sensitivity (CS), biomechanical stability and visual effects [1,2,3]
No summative conclusions were produced because there were no sufficient qualified studies for systematic analysis, and heterogeneity existed in the outcome indicators and follow-up duration of each study, making the results biased to some extent
Summary
To compare the postoperative safety, efficacy, predictability, visual quality and biomechanics after implantation of Artisan vs. Artiflex phakic intraocular lenses (PIOLs). Of various PIOLs having been designed, Artisan and Artiflex lenses, considered to. Both of them are implanted in the same location and fixated directly to the iris tissue, but they differ in material properties and surgical incision size [5]. A number of clinical trials [4, 5, 7,8,9,10,11,12,13,14,15] comparing Artisan with Artiflex PIOLs for moderate to high myopia were conducted to obtain broader and. No summative conclusions were produced because there were no sufficient qualified studies for systematic analysis, and heterogeneity existed in the outcome indicators and follow-up duration of each study, making the results biased to some extent
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