Abstract

Background and Aim: Artificial oocyte activation (AOA) can be used to induce the calcium oscillations required for oocyte activation. Using calcium ionophores for AOA has been shown to overcome fertilisation failure in cases attributed to failed oocyte activation. It was recently suggested that AOA may also restore calcium signalling deficiencies in cleavage stage embryos which arrest in cases of failed blastocyst development (Ebner et al. 2015). This study investigated the effects of AOA on 34 patients with previous poor or failed blastocyst development between the period July 2018 and January 2020.

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