Abstract

Orthopantomogram (OPG) is important for primary diagnosis of temporomandibular joint osteoarthritis (TMJOA), because of cost and the radiation associated with computed tomograms (CT). The aims of this study were to develop an artificial intelligence (AI) model and compare its TMJOA diagnostic performance from OPGs with that of an oromaxillofacial radiology (OMFR) expert. An AI model was developed using Karas’ ResNet model and trained to classify images into three categories: normal, indeterminate OA, and OA. This study included 1189 OPG images confirmed by cone-beam CT and evaluated the results by model (accuracy, precision, recall, and F1 score) and diagnostic performance (accuracy, sensitivity, and specificity). The model performance was unsatisfying when AI was developed with 3 categories. After the indeterminate OA images were reclassified as normal, OA, or omission, the AI diagnosed TMJOA in a similar manner to an expert and was in most accord with CBCT when the indeterminate OA category was omitted (accuracy: 0.78, sensitivity: 0.73, and specificity: 0.82). Our deep learning model showed a sensitivity equivalent to that of an expert, with a better balance between sensitivity and specificity, which implies that AI can play an important role in primary diagnosis of TMJOA from OPGs in most general practice clinics where OMFR experts or CT are not available.

Highlights

  • Orthopantomogram (OPG) is important for primary diagnosis of temporomandibular joint osteoarthritis (TMJOA), because of cost and the radiation associated with computed tomograms (CT)

  • This study aimed to investigate the clinical utility of an artificial intelligence (AI) diagnostic tool developed for TMJOA diagnosis from OPG using deep learning that compared the AI read with that of an expert

  • The recall value of TMJOA was 0. 51, which means that the model predicted TMJOA in patients with actual TMJOA about half the time in Trial 1

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Summary

Introduction

Orthopantomogram (OPG) is important for primary diagnosis of temporomandibular joint osteoarthritis (TMJOA), because of cost and the radiation associated with computed tomograms (CT). The orthopantomogram (OPG) is the most common examination method used for screening various lesions and conditions in the maxillofacial region, while it is less able to identify bony changes in the TMJ structure that are small in size and overlapped by other skull s­ tructures[5]. This makes OPG useful for screening examinations that experienced experts such as oromaxillofacial radiology (OMFR) or orofacial pain specialists read and recommend, if necessary, an additional CBCT to confirm a diagnosis. This study aimed to investigate the clinical utility of an AI diagnostic tool developed for TMJOA diagnosis from OPG using deep learning that compared the AI read with that of an expert

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