Abstract
The development of artificial intelligence (AI) algorithms has permeated the medical field with great success. The widespread use of AI technology in diagnosing and treating several types of cancer, especially colorectal cancer (CRC), is now attracting substantial attention. CRC, which represents the third most commonly diagnosed malignancy in both men and women, is considered a leading cause of cancer-related deaths globally. Our review herein aims to provide in-depth knowledge and analysis of the AI applications in CRC screening, diagnosis, and treatment based on current literature. We also explore the role of recent advances in AI systems regarding medical diagnosis and therapy, with several promising results. CRC is a highly preventable disease, and AI-assisted techniques in routine screening represent a pivotal step in declining incidence rates of this malignancy. So far, computer-aided detection and characterization systems have been developed to increase the detection rate of adenomas. Furthermore, CRC treatment enters a new era with robotic surgery and novel computer-assisted drug delivery techniques. At the same time, healthcare is rapidly moving toward precision or personalized medicine. Machine learning models have the potential to contribute to individual-based cancer care and transform the future of medicine.
Highlights
Artificial intelligence (AI) is the field of computer sciences devoted to building smart machines capable of performing tasks that typically require human-level intelligence [1]
The present study revealed that the combination of this model and fecal occult blood test (FOBT) contributed to a 2.1-fold increase in cancer detection in the Israeli dataset
Even though the colonoscopy is widely accepted as the “gold-standard” of colorectal cancer (CRC) screening methods, it is worth mentioning that the current procedure is not 100% sensitive
Summary
Artificial intelligence (AI) is the field of computer sciences devoted to building smart machines capable of performing tasks that typically require human-level intelligence [1]. When used to test for the v-raf murine sarcoma viral oncogene homolog B1 (BRAF) V600E mutation in colorectal carcinomas, the current model demonstrated 100% diagnostic sensitivity, 87.5% diagnostic specificity and 93.8% diagnostic accuracy This novel approach, which was based on near-infrared (NIR) spectroscopy in conjunction with counter propagation artificial neural network (CP-ANN), can help distinguish between the BRAF V600E mutant and the wild type. A few years later, Wang et al [12] combined gene expression profiling data from The Cancer Genome Atlas (TCGA) database and analysis with AI algorithms to improve CRC diagnosis They used BP and learning vector quantization (LVQ) neural networks to build four diagnostic models; Cancer/Normal, M0/M1, carcinoembryonic antigen (CEA) testing (
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