Abstract

<p indent="0mm">Despite significant progress, modern biology research is facing a huge bottleneck in its development due to lack of revolutionary theoretical frameworks. The rapid development of artificial intelligence (AI) based on big data and deep learning is spurring “Biology V3.0”—Artificial intelligence biology (AI Biology, AIBIO). We define AI Biology as the science of using the principles and means of AI to study the basic laws of living systems. AI Biology is characterized by its ability to integrate multi-dimensions and multi-factors involved in the dynamic process of intermolecular interactions and regulations, so as to truly understand the basic principles in life sciences. As a new life science discipline, AI Biology has the potential to fundamentally change the existing paradigm of biological research, to expand both the connotation and the complexity of biological research, to answer some of the fundamental questions in biological science, and to achieve substantial breakthroughs in key areas of life science and medical science.

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