Abstract
Advances in Artificial Intelligence (AI) offer new Information Technology (IT) opportunities in various applications and fields (industry, health, etc.). The medical informatics scientific community expends tremendous effort on the management of diseases affecting vital organs making it a complex disease (lungs, heart, brain, kidneys, pancreas, and liver). Scientific research becomes more complex when several organs are simultaneously affected, as is the case with Pulmonary Hypertension (PH), which affects both the lungs and the heart. Therefore, early detection and diagnosis of PH are essential to monitor the disease's progression and prevent associated mortality. The issue addressed relates to knowledge of recent developments in AI approaches applied to PH. The aim is to provide a systematic review through a quantitative analysis of the scientific production concerning PH and the analysis of the networks of this production. This bibliometric approach is based on various statistical, data mining, and data visualization methods to assess research performance using scientific publications and various indicators (e.g., direct indicators of scientific production and scientific impact). The main sources used to obtain citation data are the Web of Science Core Collection and Google Scholar. The results indicate a diversity of journals (e.g., IEEE Access, Computers in Biology and Medicine, Biology Signal Processing and Control, Frontiers in Cardiovascular Medicine, Sensors) at the top of publications. The most relevant affiliations are universities from United States of America (Boston Univ, Harvard Med Sch, Univ Oxford, Stanford Univ) and United Kingdom (Imperial Coll London). The most cited keywords are "Classification", "Diagnosis", "Disease", "Prediction", and "Risk". This bibliometric study is a crucial part of the review of the scientific literature on PH. It can be viewed as a guideline or tool that helps researchers and practitioners to understand the main scientific issues and challenges of AI modeling applied to PH. On the one hand, it makes it possible to increase the visibility of the progress made or the limits observed. Consequently, it promotes their wide dissemination. Furthermore, it offers valuable assistance in understanding the evolution of scientific AI activities applied to managing the diagnosis, treatment, and prognosis of PH. Finally, ethical considerations are described in each activity of data collection, treatment, and exploitation to preserve patients' legitimate rights.
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