Artificial Intelligence Algorithm-Based Computed Tomography Image in Assessment of Acute Renal Insufficiency of Patients Undergoing Percutaneous Coronary Intervention.

Xiuming Zhang,Chunhua Tian,Tao Liu,M Pallikonda Rajasekaran

doi:10.1155/2022/2214583

Abstract

This study was aimed to analyze the changes in renal function of patients undergoing percutaneous coronary intervention (PCI) surgery and the characteristics of their computed tomography (CT) image based on artificial intelligence algorithms. In this study, 104 patients with coronary atherosclerotic heart disease (CAHD) were treated as the research objects. They were divided into an experimental group (patients who underwent CAG and PCI within 1 week after enhanced coronary CT (ECCT)) and the control group (patients who underwent CAG and PCI within 1–3 weeks after ECCT). Renal imaging scans of patients were performed by CT based on discrete inseparable shear transform (DNST) optimized algorithm, which was named as O-DNST. The results showed that the serum creatinine (Scr), blood urea nitrogen (BUN), and urine protein (UP) levels of patients in the experimental group were significantly higher than those of the control group 24–72 hours after surgery, while the levels of endogenous creatinine clearance (Ccr) and estimated glomerular filtration rate (eGFR) were significantly lower than those of the control group (P < 0.05). The levels of β2 microglobulin (β2-MG), C-reactive protein (CRP), interleukin 6 (IL-6), and tumor necrosis factor (TNF-α) in the experimental group were significantly higher than those in the control group 24–72 hours after surgery (P < 0.05). The incidence of contrast-induced nephropathy (CIN) in the experimental group (15.38%) was significantly higher than that in the control group (5.8%), and the difference was statistically significant (P < 0.05). The results showed that repeated application of contrast agent in a short period of time can promote the increase of serum inflammation levels in PCI patients, which may be a risk factor for CIN in PCI patients.

Highlights

Coronary atherosclerotic heart disease (CAHD) is caused by atherosclerotic lesions in coronary arteries that cause stenosis or obstruction of the vascular lumen, resulting in myocardial ischemia, hypoxia, or necrosis, so it is often referred to as “coronary heart disease (CHD)” [1]
104 patients with CAHD who underwent coronary angiography (CAG) and Percutaneous coronary intervention (PCI) surgery after the enhanced coronary CT (ECCT) were treated as the research objects. ey were divided into an experimental group and the control group. e preoperative and postoperative renal function indicators, inflammatory indicators, and the incidence of contrast-induced nephropathy (CIN) in the two groups were compared to deeply analyze the clinicopathological characteristics of acute renal function injury caused by the application of contrast agents in PCI surgery, aiming to provide reference for selection of clinical prevention and treatment strategies for CIN
104 patients with CAHD who underwent CAG and PCI surgery in hospital from March 2018 to May 2021 were selected as the research subjects after coronary CT examination with enhanced coronary artery. ere were 58 males and 46 females, with an age range of 20–72 years. is study had been approved by the ethics committee of the hospital, and the patients and their family members had understood the research situation and signed the informed consent forms

Summary

Introduction

Coronary atherosclerotic heart disease (CAHD) is caused by atherosclerotic lesions in coronary arteries that cause stenosis or obstruction of the vascular lumen, resulting in myocardial ischemia, hypoxia, or necrosis, so it is often referred to as “coronary heart disease (CHD)” [1]. E treatment of CHD mainly includes drug therapy, interventional therapy, and surgical coronary artery bypass graft. Coronary artery bypass grafting refers to the use of the patient’s own great saphenous vein or other arteries to connect the distal end of the narrowed coronary artery with the aorta to supply blood to the distal end of the myocardium to improve the symptoms of angina pectoris and improve life treatment, but the operation is Contrast Media & Molecular Imaging complicated and risky [7]. Percutaneous coronary intervention (PCI) has the advantages of simple operation, small trauma area, and quick postoperative recovery. It can quickly rebuild coronary blood vessels in emergency situations, which can effectively alleviate the symptoms of patients and improve the quality of life [8]

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Discussion

Conclusion