Abstract
Significant artifacts arise in T 1 ρ -weighted imaging when nutation angles suffer small deviations from their expected values. These artifacts vary with spin-locking time and amplitude, severely limiting attempts to perform quantitative imaging or measurement of T 1 ρ relaxation times. A theoretical model explaining the origin of these artifacts is presented in the context of a T 1 ρ -prepared fast spin-echo imaging sequence. Experimentally obtained artifacts are compared to those predicted by theory and related to B 1 inhomogeneity. Finally, a “self-compensating” spin-locking preparatory pulse cluster is presented, in which the second half of the spin-locking pulse is phase-shifted by 180°. Use of this pulse sequence maintains relatively uniform signal intensity despite large variations in flip angle, greatly reducing artifacts in T 1 ρ -weighted imaging.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
