Abstract
f this method were as follows: 1) suffiient number of cells for observation can e obtained; 2) the quality is not reduced by rying or smearing procedures; 3) although he oral mucosa bleeds easily, such bleedng does not result in unclear regions; 4) bservation is possible even in cases in hich a cancerous background, such as ecrotic tissue or cancer-related findings such as Candida infection), is not resolved ompletely; 5) deep-layer squamous cells an be collected relatively easily even in umours presenting exophytic type; and 6) his method causes less cellular overlap nd is useful for morphological analyses, mmunohistochemical staining and moleclar biological analyses. onclusion: The observations discussed bove indicate that liquid-based cytology s a highly useful system.
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