Abstract

Dioxins are recalcitrant anthropogenic contaminants that only a few bacteria are known to degrade. A recent study by Mutter and Zylstra (e01067-21) resolves the metabolic pathways used by Sphingomonas wittichii RW1 to metabolize the related compounds dibenzo-p-dioxin and dibenzofuran. While the same dioxygenase is responsible for initiating the degradation of these two compounds, separate enzymes are required for all the following steps in the two catabolic pathways.

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