Abstract
Pseudomonas aeruginosa and Staphyloccocus aureus are among the most important pathogens in polymicrobial infections, and their co-occurrence is linked to outcomes that are more severe than those of the respective monospecies infections. There is great interest in understanding how these two species interact and the consequences of those interactions for the host. Work by Niggli and Kümmerli (e00962-20) showed that ecological factors such as strain genetic background, relative species frequency, and environmental conditions are important elements governing population dynamics and species coexistence patterns. An improved understanding of what influences these interspecies interactions may provide a basis for better treatment of polymicrobial infections.
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