Abstract
At disease onset children with acute lymphoblastic leukemia (ALL) may present with arthralgia (join pain) or even signs of arthritis with joint swelling, redness, and restriction of motion. This might cause misdiagnosis and thereby lead to prolonged diagnostic delay. The present study aimed to identify ALL children with joint involvement and to compare their characteristics and outcome with ALL children without joint involvement.
Highlights
At disease onset children with acute lymphoblastic leukemia (ALL) may present with arthralgia or even signs of arthritis with joint swelling, redness, and restriction of motion
The present study aimed to identify ALL children with joint involvement and to compare their characteristics and outcome with ALL children without joint involvement
The overall and event-free survival were superior compared to the children without joint involvement
Summary
At disease onset children with acute lymphoblastic leukemia (ALL) may present with arthralgia (join pain) or even signs of arthritis with joint swelling, redness, and restriction of motion. This might cause misdiagnosis and thereby lead to prolonged diagnostic delay. The present study aimed to identify ALL children with joint involvement and to compare their characteristics and outcome with ALL children without joint involvement
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