Abstract
Spontaneously hypertensive rat is a good model fashion for the production of arteriosclerotic lesions in peripheral arterial trees of rat. Common carotid arteries and sinus areas and peripheral arterial trees are well recognized sites of predilection for arteriosclerosis and this arteriosclerotic lesion produces the vascular walls rigid in high-fat diet fed hypertensive rats. Blood pressure response after sinoaortic denervation gives very low response or no response at all according to the grade of severity of arteriosclerotic lesions.
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