Abstract
Systemic autoinflammatory diseases (SAD) are characterized by the presence of acute, recurrent or persistent inflammatory episodes, in which autoimmune, infectious or neoplastic causes are not evidenced. Systemic inflammation has been linked to development and progression of atherosclerosis. In the case of the Muckle Wells Syndrome (MWS), inflammation would be determined by hyperactivation of interleukin 1β (IL-1β). We present a case report in which vascular complications associated with early atherosclerosis in the MWS are described.
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