Arterial Occlusion from Anti-Jo1 Antibody-associated Autoimmune Myositis: Arteritis not Compartment Syndrome

Abstract

We present a case of arterial occlusion secondary to polymyositis associated with anti-Jo1 antibodies. A 44 year old lady presented with thigh pain and myositis associated with anti-Jo1 antibody positivity. She developed critical lower limb ischaemia with normal compartment pressures but occlusive disease on angiography. Management was with steroids and methotrexate with amputation of three digits. This case illustrates adult arteritis in the presence of acute polymyositis and anti-Jo1 antibodies as a rare yet diagnostically challenging cause of arterial ischaemia.