Arterial hypertension: The role of gut microbiota

Abstract

Pathogenesis of arterial hypertension (HTN) was predominantly associated with genetics and epigenetics, environment and disturbances in homeostasis systems (autonomous nervous system, immunity, renin-angiotensin system) for a long time. Gut microbiota has recently emerged as a self-controlled factor contributing to or limiting the development of HTN. New data on the role of gut bacteria in the development of HTN, direct blood pressure regulation as well as impact on epigenetics, immunity and renin-angiotensin-aldosterone system of its metabolites are presented.