Abstract
Arterial hypertension syndrome sustained by an unexpected association of pheochromocytoma and vesicoureteral reflux nephropathy
Highlights
Refractory high blood pressure (HBP) is a serious disease associated with a high cardiovascular risk
We report the case of a patient with refractory HBP sustained by an unexpected combination of a pheochromocytoma (PCC) and reflux nephropathy
While reflux nephropathy is responsible for renal parenchymal HBP in 40% of cases, a pheochromocytoma (PCC) is the cause of only 0.1 to 6% of HBP cases [5]
Summary
Refractory high blood pressure (HBP) is a serious disease associated with a high cardiovascular risk. It was evident from the ultrasound that the left kidney was totally destroyed and almost certainly non-functional; it was assumed to be responsible for the refractory hypertension, in addition to renal parenchymal disease due to VUR. These conditions led to surgical kidney removal. Adrenal mass examination revealed a highly vascularized tumor proliferation madeof layers of enlarged cells provided with abundant cytoplasm (Figure 2B). A) Histopathological examination of the resected kidney: marked tubular atrophy with secondary sclerosis of the glomeruli (Trichrome, x200) B) Histopathological examination of the adrenal mass: highly vascularized tumor proliferation made of layers of enlarged cells provided with abundant cytoplasm (H&E, x200). From the day after the operation until her recent 10 month postoperative follow-up, the patient had normal blood pressure and was not prescribed any anti-hypertensive medication
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