Abstract
Non-invasive evaluation of peripheral perfusion may be useful in many contexts including clinical research. We validated a novel non-invasive spectroscopy technique to quantify forearm arterial inflow. This method, which is based on the measurement of tissular total hemoglobin variations after an ischemic period, was compared to strain gauge plethysmography (SGP). The technique uses near-infrared spectroscopy (NIRS) to determine the rate of change of forearm tissue oxygenation during reactive hyperemia. In this study, 13 subjects were simultaneously evaluated with NIRS and SGP. Nine baseline flow measurements were performed to assess the reproducibility of each method. Twenty-seven serial measurements were then made to evaluate flow variation during forearm reactive hyperemia. SGP and NIRS methods showed excellent reproducibility with the same intra-class correlation coefficients (0.98). In conclusion, the NIRS technique appears well suited for non-invasive evaluation of quantitative arterial forearm flow.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.