Arterial blood gas test to decide whether to reconstruct single or both the arteries in living donor liver transplantation.

Abstract

The graft used in living donor liver transplantation (LDLT) sometimes has two hepatic arteries. This study aimed to introduce arterial-blood gas (ABG) test on the decision on whether to reconstruct a single or both arteries in LDLT. Patients with a right lobe graft with two hepatic arteries were enrolled from the prospectively maintained database of our institution. After anastomosis of one of two arteries, the back-bleeding from the second hepatic artery was taken for ABG test. Depending on the results, the second artery was anastomosed or ligated. Between January 2012 and December 2017, a total of 372 patients underwent LDLT, and 21 living donors had two right hepatic arteries. Based on ABG test results, a single anastomosis was created in 15 recipients while double anastomoses were performed in the remaining 6 recipients. All the patients had an uneventful recovery and were discharged in good conditions. Neither hepatic artery thrombosis nor liver dysfunction was observed during the median follow-up of 26 months (range, 6-71 months). The overall incidence of biliary complications was 9.5% (2/21). Bile leakage arose in one patient with two hepatic artery reconstructions, and the patient subsequently developed biliary stricture. Biliary stricture occurred in another patient with one hepatic artery reconstruction. The biliary complications were successfully managed with endoscopic or percutaneous intervention. ABG test provides a good measure for deciding whether to reconstruct single or both arteries in LDLT.