Abstract
Free radical scavenging activity, total phenolic content and the chemical composition of the essential oil isolated by steam distillation from Artemisia dracunculus L. was investigated. The isolation yield was 0.24% (v/w) based on the fresh plant material (leaves). GC-MS investigation identified 21 components, accounting 99.93% of the total amount. The major components were sabinene (42.38%), isoelemicin (12.91%), methyl eugenol (9.09%), elemicin (7.95%) and beta-ocimene (6.46%). The free radical scavenging activity of the essential oil of Artemisia dracunculus L. was evaluated in vitro by the DPPH assay (IC50 = 0.730 � 0.213 mg/mL), BHA and alpha-tocopherol were used as a positive control. The total phenolic content of the tarragon essential oil was evaluated by the Folin-Ciocalteu method (GAE = 0.451 � 0.001 mg/g sample). In view of these data, we consider that tarragon essential oil could represent a new antioxidants source as a reliable option to reduce the usage of synthetic additives.
Highlights
Chemical composition and antioxidant propertiesARIADNA PETRONELA FILDAN1,2, IOAN PET3, DANIELA STOIN4, GABRIEL BUJANCA4, ALEXANDRA TEODORA LUKINICH-GRUIA5, CALIN JIANU4*, ADELINA MARIA JIANU6*, MATILDA RADULESCU6, DOINA ECATERINA TOFOLEAN1,7 1Ovidius University, Faculty of Medicine, 124 Mamaia Blvd., 900527, Constana, Romania 2Constanta Clinical Pulmonology Hospital, 167 Alexandru Lapusneanu Blvd., 900001, Constanta, Romania 3Banat’s University of Agricultural Sciences and Veterinary Medicine King Michael I of Romania from Timisoara, Faculty of Bioengineering of Animal Resources, 119 Calea Aradului, 300645, Timisoara, Romania 4Banat’s University of Agricultural Sciences and Veterinary Medicine King Michael I of Romania from Timisoara, Faculty of Food Engineering,119 Calea Aradului, 300645, Timisoara, Romania 5OncoGen Centre, County Hospital Pius Branzeu, 156 Liviu Rebreanu Blvd., 300736, Timisoara, Romania 6University of Medicine and Pharmacy Victor Babes, Faculty of Medicine, 2nd Eftimie Murgu Sq., 300041 Timisoara, Romania 7County Clinical Emergency Hospital of Constanta, 145 Tomis Blvd., 900591, Constanta, Romania
Free radical scavenging activity, total phenolic content and the chemical composition of the essential oil isolated by steam distillation from Artemisia dracunculus L. was investigated
The major compounds were sabinene (42.38%), isoelemicin (12.91%), methyl eugenol (9.09%), elemicin (7.95%) and beta-ocimene (6.46%)
Summary
ARIADNA PETRONELA FILDAN1,2, IOAN PET3, DANIELA STOIN4, GABRIEL BUJANCA4, ALEXANDRA TEODORA LUKINICH-GRUIA5, CALIN JIANU4*, ADELINA MARIA JIANU6*, MATILDA RADULESCU6, DOINA ECATERINA TOFOLEAN1,7 1Ovidius University, Faculty of Medicine, 124 Mamaia Blvd., 900527, Constana, Romania 2Constanta Clinical Pulmonology Hospital, 167 Alexandru Lapusneanu Blvd., 900001, Constanta, Romania 3Banat’s University of Agricultural Sciences and Veterinary Medicine King Michael I of Romania from Timisoara, Faculty of Bioengineering of Animal Resources, 119 Calea Aradului, 300645, Timisoara, Romania 4Banat’s University of Agricultural Sciences and Veterinary Medicine King Michael I of Romania from Timisoara, Faculty of Food Engineering,119 Calea Aradului, 300645, Timisoara, Romania 5OncoGen Centre, County Hospital Pius Branzeu, 156 Liviu Rebreanu Blvd., 300736, Timisoara, Romania 6University of Medicine and Pharmacy Victor Babes, Faculty of Medicine, 2nd Eftimie Murgu Sq., 300041 Timisoara, Romania 7County Clinical Emergency Hospital of Constanta, 145 Tomis Blvd., 900591, Constanta, Romania. Total phenolic content and the chemical composition of the essential oil isolated by steam distillation from Artemisia dracunculus L. was investigated. The free radical scavenging activity of the essential oil of Artemisia dracunculus L. was evaluated in vitro by the DPPH assay (IC50 = 0.730 ± 0.213 mg/mL), BHA and alpha-tocopherol were used as a positive control. The total phenolic content of the tarragon essential oil was evaluated by the Folin-Ciocalteu method (GAE = 0.451 ± 0.001 mg/g sample). Our study aimed to determine: i) the chemical composition and ii) radical scavenging activity and total phenolic content of the EO isolated from A. dracunculus leaves on which there are no previous studies
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