[Artículo traducido] Pitiriasis rubra pilaris: serie de casos multicéntrica de 65 pacientes españoles

Abstract

IntroductionPRP is a rare entity of unknown etiopathogenesis. Lack of management guidelines makes it a challenge for clinicians. ObjectiveTo add our experience to increase evidence about PRP. MethodsWe performed a retrospective, descriptive and multicentric study of 65 patients with PRP, being the largest European case series of patients with PRP. ResultsPRP was more frequent in male patients with an average age of 51 years, but erythrodermic forms presented in older patients (average age 61 years).Six (75%) paediatric patients and ten (60%) non-erythrodermic adults controlled their disease with topical corticosteroids. On the contrary, 26 (68%) erythrodermic patients required biologic therapy as last and effective therapy line requiring an average of 6.5 months to achieve complete response. ConclusionOur study showed a statistical difference in terms of outcome and response to treatment between children or patients with limited disease and patients who develop erythroderma.