Abstract
scholarly articles on cardiology Journal of Cardiology & Cardiovascular Therapy is an Open Access, international peer reviewed journal launched from Juniper Publishers. Cardiology is a branch of medicine deals with the disorders of heart that keeps cardiologists up to date with advances in the diagnosis and treatment of cardiovascular diseases.
Highlights
Chagas’ disease (ChD), known as American trypanosomiasis, is a serious chronically debilitating and often fatal human endemic infectious-parasitic affection caused by Trypanosoma cruzi, transmitted through a hematophagous triatomine vector [1]
The mechanistic studies identifying i) the mediators produced by cardiomyocytes in response to Trypanosoma cruzi infection, that may trigger the migration of leukocytes and other cells to the heart; ii) the signaling mechanisms regulated by the inflammatory cytokines (e.g. Tumour Necrosis Factor-α (TNF-α) and IL-1) that may evoke cell survival/cell growth or cell death responses in chagasic myocardium; and iii) the destructive effects of “oxidative burst” of activated inflammatory cells in Chagas heart disease (ChHD), are discussed elsewhere [35]
It is reasonable to speculate that reactive oxygen species (ROS) can be regarded as a potential driver of cardiac arrhythmia in ChHD
Summary
Chagas’ disease (ChD), known as American trypanosomiasis, is a serious chronically debilitating and often fatal human endemic infectious-parasitic affection caused by Trypanosoma cruzi, transmitted through a hematophagous triatomine vector [1]. J Cardiol & Cardiovasc Ther 14(2): JOCCT.MS.ID.555881 (2019)
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