Abstract

ABSTRACTObjective To compare the results of two slings, Argus T® and Advance®, for the treatment of postprostatectomy urinary incontinence (PPUI). Material and Methods: From December 2010 to December 2011, 22 patients with PPUI were randomized as follows: 11 (mean age 62.09(±5.30)) underwent treatment with Advance® and 11 (mean age 62.55(±8.54)) with Argus T®. All patients were evaluated preoperatively with urodynamic testing, quality of life questionnaire (ICIQ-SF), voiding diary and 24-hour pad test. Exclusion criteria were: neurological diseases, severe detrusor overactivity and urethral stenosis. Evaluation was performed at 6, 12 and 18 months after the surgery. After implantation of the Argus T® sling, patients who experienced urine leakage equal to or greater than the initial volume underwent adjustment of the sling tension. Results were statistically analyzed using the Fisher’s test, Kolmogorov-Smirnov test, Friedman’s non-parametric test or the Mann-Whitney test.Results Significant improvement of the 24-hour pad test was observed with the Argus T® sling (p=0.038) , With regard to the other parameters, there was no significant difference between the two groups. Removal of the Argus T® device due to perineal pain was performed in one patient (9%). Despite non uniform results, both devices were considered useful to improve quality of life (ICIQ-SF): Argus T® (p=0.018) and Advance® (p=0.017).Conclusions Better results were observed in the 24h pad test and in levels of satisfaction with the Argus T® device. Both slings contributed to improve quality of life (ICIQ-SF), with acceptable side effects.

Highlights

  • Post-prostatectomy urinary incontinence (PPUI) is a common complication of surgical treatment in patients with prostate cancer or benign prostatic hyperplasia

  • It’s occurrence has a negative impact on quality of life (QoL) and decrease the benefit of the treatment of primary disease [1, 2]

  • Two suburethral slings (SUS) were available in the Brazilian market at the time of recruiting for this research: ibju | Argus T ® versus Advance ® Sling for postprostatectomy urinary incontinence

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Summary

Introduction

Post-prostatectomy urinary incontinence (PPUI) is a common complication of surgical treatment in patients with prostate cancer or benign prostatic hyperplasia. PPUI prevalence varies from 2.5% to 67%. This is due to the wide variation in studies, such as non-standardized definition, type of surgical technique, diagnostic assessment, patient selection and outcome measures [3]. Suburethral slings (SUS) have been re-designed and attracted particular interest due to its promising and durable results [3], even in face of the higher good results of the Artificial Urinary Sphincter-AUS 800® (USA). Two SUSs were available in the Brazilian market at the time of recruiting for this research: ibju | Argus T ® versus Advance ® Sling for postprostatectomy urinary incontinence

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