Abstract
Reporting recently in Nature and Nature Structural and Molecular Biology, Shen etal. (2013) and Smibert etal. (2013) uncover mechanisms for Argonaute (Ago) protein regulation. Smibert etal. find that microRNA availability controls Ago levels, and Shen etal. show that epidermal growth factor receptor-mediated Ago2 phosphorylation affects Ago loading.
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