Argon Laser Photocoagulation Combined With Subconjunctival and Intravitreal Bevacizumab Injections for a Retrocorneal Neovascular Membrane

Abstract

Purpose: To report a case of retrocorneal membrane effectively treated with focal argon laser photocoagulation combined with subconjunctival and intravitreal bevacizumab injections. Case summary: A 69-year-old female presented with persistent ocular pain and decreased visual acuity of the right eye following a complicated extracapsular cataract extraction performed nine months earliet. On examination, there was a neovascular retrocorneal membrane covering the superior one-third of the cornea with a sutured wound along the limbus. Following unresponsive conservative treatment, we performed focal argon laser photocoagulation followed by subconjunctival and intravitreal bevacizumab injections (1.25 mg). Two weeks later, markedly regressed neovascularization was noted. Additional argon laser photocoagulation, subconjunctival and intravitreal bavacizumab were performed six weeks later. Four months after the last treatment, the neovascular component substantially decreased and fibrous scar tissue replaced the neovascularization. The retrocorneal membrane showed no progression.