Arginine Metabolism in Dental Plaque Is Associated With Tooth Surface Dental Caries Status

Abstract

Article title and bibliographic information Oral arginine metabolism may decrease the risk for dental caries in children. Nascimento MM, Liu Y, Kalra R, Perry S, Adewumi A, Xu X, Primosch RE, Burne RA. J Dent Res 2013;92(7):604-8. Reviewer Walter A. Bretz, DDS, PhD Purpose/Question The main purpose of this study was to determine the relationship between oral arginine metabolism in dental plaque (assayed by the activity of the arginine deiminase system [ADS]) and caries experience, tooth surface caries status, and dentition type. Source of funding This work was supported by the University of Florida College of Dentistry and by the National Institute of Dental and Craniofacial Research (Grant DE10362 ). Type of study/Design Cross-sectional study Level of evidence Level 2: Limited-quality, patient-oriented evidence Strength of recommendation grade Not applicable