Abstract

Arene oxides and trans-dihydrodiols at the 5,6- and 7,8-positions of quinoline have been synthesized. High stability of both arene oxides allowed identification of the 5,6-oxide as a liver microsomal metabolite of quinoline. Both arene oxides are converted to trans-dihydrodiols by microsamal epoxide hydrolase.

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call