Abstract
The synthesis of 6- epi-COTC, a diastereoisomer of Streptomyces metabolite 2-crotonyloxymethyl-(4 R,5 R,6 R)-4,5,6-trihydroxycyclohex-2-enone (COTC), is described. The anti-cancer activities of the novel analogue, in racemic and enantiomerically pure forms, are presented.
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